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Explore our curated collection of research, FAQs, and practical resources — all grounded in the latest metabolic health science.
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Evidence library
RCTs comparing low-carb to low-fat
When randomised controlled trials directly compared low-carb and low-fat interventions, the results were striking. This table has become one of PHC's most-referenced pieces of evidence.
Randomised controlled trials reviewed
Significantly favoured low-carb
Significantly favoured low-fat
PHC summary of 67 RCTs comparing low-carbohydrate to low-fat interventions for weight, HbA1c and lipid markers — published February 2019.
Featured research
Key studies that support real food approaches to metabolic health.
Dr Unwin's 6-Year Results in Type 2 Diabetes Remission
BMJ Nutrition, Prevention & Health
Over 6 years at a single NHS practice, 46% of patients with type 2 diabetes who adopted a low-carbohydrate approach achieved drug-free remission, with an average HbA1c reduction of 19 mmol/mol and sustained weight loss.
Read on publisher’s siteAmbassador Evaluation Study
BMJ Nutrition, Prevention & Health
Evaluation of PHC's volunteer-led Real Food Lifestyle courses across UK GP surgeries: participants saw significant improvements in weight, blood pressure and HbA1c, validating community-delivered lifestyle intervention as a scalable NHS model.
Read on publisher’s siteDietary Strategies for Remission of Type 2 Diabetes
Journal of Human Nutrition and Dietetics (BDA)
A systematic review endorsed by the British Dietetic Association concluding that low-carbohydrate and low-energy dietary approaches are both effective routes to type 2 diabetes remission — giving clinicians more than one evidence-based option.
Read on publisher’s siteAll 18 research papers
Every paper and summary PHC references, from peer-reviewed journals to our own evidence reports.
- 01
Healthy Eating Guidelines & Weight Loss Advice for the UK
PHC Report·2016
- 02
Ambassador & Healthcare Professionals Case Study Book
PHC Report·2018
- 03
RCTs Table Comparing Low-Carb to Low-Fat Diets (67 RCTs; 36 favoured low-carb, 0 favoured low-fat)
PHC Summary·2019
- 04
RCTs Table Comparing Low-Carb to Low-Fat Diets with Type 2 Diabetes
PHC Summary·2019
- 05
Eat Fat, Cut the Carbs and Avoid Snacking to Reverse Obesity and Type 2 Diabetes
National Obesity Forum·2016
- 06
Dr Unwin's 6-Year Results in Type 2 Diabetes Remission
BMJ Nutrition, Prevention & Health·2020
- 07
Ambassador Evaluation Study
BMJ Nutrition, Prevention & Health·2020
- 08
Healthcare Professional Qualitative Study
BMJ Nutrition, Prevention & Health·2021
- 09
Adapting Diabetes Medication for Low-Carbohydrate Diets
British Journal of General Practice·2019
- 10
Dietary Strategies for Remission of Type 2 Diabetes
Journal of Human Nutrition and Dietetics (BDA)·2021
- 11
Dr David Unwin Obesity Editorial
BMJ Nutrition, Prevention & Health·2023
- 12
Low carbohydrate and psychoeducational programs show promise for the treatment of ultra-processed food addiction
Frontiers in Psychiatry·2022
- 13
What predicts drug-free type 2 diabetes remission? Insights from an 8-year general practice service evaluation of a lower carbohydrate diet with weight loss
BMJ Nutrition, Prevention & Health·2023
- 14
Understanding the experiences of ketogenic metabolic therapy for people living with varying levels of depressive symptoms: a thematic analysis
Frontiers in Nutrition·2024
- 15
A feasibility and acceptability study of Liberate: an online, peer-supported, psychoeducational intervention for ultra-processed food addiction
Frontiers in Psychiatry·2025
- 16
Integrating the management of ultra-processed food addiction into type 2 diabetes care: a clinical response to De Silva et al. (2025) and practical recommendations for practitioners
Frontiers in Psychiatry·2026
- 17
Effect of a low-carbohydrate diet on glycaemic control and disease management in type 2 diabetes: results from a prospective free-living trial
BMJ Nutrition, Prevention & Health·2026
- 18
Changes in binge eating symptoms following an online community-based ultra-processed food addiction intervention: Liberate
Frontiers in Public Health·2026
Peer-reviewed papers open on the publisher’s site. PHC summaries link to in-depth pages on this site.
Frequently asked questions
Clear, evidence-based answers to the questions we hear most often — grouped by topic.
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